Dr Alexander Fletcher
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Teaching:
Research:
| Current grants, as Principal Investigator |
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Chaste: developing sustainable software for computational biology
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Understanding self-organised tissue patterning across scales
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EPSRC |
| Current grants, as Coinvestigator |
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Hypothalamic development from self-organising progenitors
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| Past grants, as Coinvestigator |
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How do the atypical cadherins Fat and Dachsous integrate growth and patterning
during development?
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Biography:
2022 - present: Senior Lecturer, SoMaS, University of Sheffield
2019 - 2022: Lecturer, SoMaS, University of Sheffield
2015 - 2019: Vice-Chancellor's Fellow, SoMaS, University of Sheffield
2011 - 2015 : Research Fellow in Computational Science, Mathematical Institute, University of Oxford
2008 - 2015 : Stipendiary Lecturer in Mathematics, St Hugh's College, University of Oxford
2008 - 2011 : Postdoctoral Research Assistant, Mathematical Institute, University of Oxford
2005 - 2010 : DPhil, Mathematical Institute, University of Oxford
Research interests:
I develop and apply mathematical models to study complex biological systems. Techniques range from discrete and continuous models of temporal dynamics to more computationally intensive individual-based and multiscale simulations. Major applications include mechanisms underlying tissue homeostasis and their disruption in cancer formation and progression, and the orchestration of cell-level processes such as proliferation, death, adhesion and migration to give correct tissue-level proportions in embryos.